BioCryst Pharmaceuticals, Inc.
BCRX
Health Care
2
exclusion reasons
1 theme
This page is part of our public exclusion list — a transparency tool that shows which companies we screen out and why. It is not investment advice, and it is not an accusation. But it is subject to change as our understanding of the facts evolves.
BioCryst Pharmaceuticals develops and commercializes oral and injectable medicines for rare diseases. The company’s drug development pipeline and regulatory submissions require animal testing as a standard component of preclinical safety and efficacy studies, a practice explicitly referenced in its SEC filings regarding data compliance for new drug applications.
This reliance on animal models is integral to the pharmaceutical business model. While BioCryst does not manufacture equipment designed for animal harm, its core research and development activities are built upon the commercial exploitation of animals for testing, placing it under this broad exclusion category. The company has not publicly disclosed a commitment to adopting or funding non-animal testing methodologies.
BioCryst Pharmaceuticals conducts animal testing as a core component of its drug development and regulatory approval process. The company’s research pipeline, including therapies for hereditary angioedema and other rare diseases, relies on preclinical data from laboratory and animal studies to establish safety and biological activity, as documented in its SEC filings. This practice is inherent to its business model as a pharmaceutical research and development firm.
A 2022 review by Cruelty Free Investors listed BioCryst among companies that continue to test on animals. The company’s drug applications, such as the 2018 New Drug Application for a kallikrein inhibitor, included safety and efficacy data derived from animal models, as evidenced by FDA review documents. BioCryst sponsors and funds these studies directly, as seen in published Phase 3 trial materials which reference underlying preclinical animal research.
Research Sources
1 organization
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Companies appear on our exclusion list based on our investment judgment — not because they've done anything illegal. This is a difference of values and opinion, not an accusation of wrongdoing. Exclusion does not constitute a recommendation against investing in any company, and absence from the list does not constitute a recommendation to invest.
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