Crinetics Pharmaceuticals, Inc.
CRNX
Health Care
2
exclusion reasons
1 theme
This page is part of our public exclusion list — a transparency tool that shows which companies we screen out and why. It is not investment advice, and it is not an accusation. But it is subject to change as our understanding of the facts evolves.
Crinetics Pharmaceuticals conducts preclinical testing of its drug candidates on animals, including dogs, as part of its product development process. The company's research protocols have involved oral dosing studies on dogs, as documented in its scientific reports.
In April 2022, an undercover investigation focused on a dog breeding facility in Cumberland, Virginia, which supplied animals for laboratory testing. The facility was cited for numerous violations of the Animal Welfare Act. While not a Crinetics-owned operation, this investigation highlighted the supply chain conditions for dogs used in pharmaceutical testing, an industry in which Crinetics participates. The company's reliance on animal testing places it within a sector facing increasing regulatory scrutiny, as evidenced by state-level legislation like Illinois' 2023 ban on toxicity testing on dogs and cats.
Crinetics Pharmaceuticals is a clinical-stage biopharmaceutical company whose drug development pipeline relies on animal testing as a required component of regulatory submissions. The company's public filings and study protocols reference conducting animal studies in accordance with Good Laboratory Practice (GLP) regulations.
An undercover investigation in 2022 documented that Crinetics Pharmaceuticals commissioned toxicity testing of its drugs at a contract research organization, Inotiv. The investigation revealed that beagle puppies and other animals suffered and died during these procedures; some animals were immobilized by toxic effects, while others died during the tests. This specific evidence, reported by Cruelty Free Investors, links the company's research directly to animal testing practices that cause significant animal suffering.
Research Sources
1 organization
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