Skip to main content
← All exclusions

Structure Therapeutics

GPCR

Health Care

2

exclusion reasons

1 theme

Animal Welfare (2)
GPCR Health Care Current as of March 2026

Structure Therapeutics is screened out under 2 exclusion reasons spanning 1 issue category.

This page is part of our public exclusion list — a transparency tool that shows which companies we screen out and why. It is not investment advice, and it is not an accusation. It is a statement of values.

Animal Testing & Research
Since Mar 3, 2025

Structure Therapeutics is a clinical-stage biotechnology company developing oral small molecule therapeutics for metabolic and cardiometabolic diseases. Its lead candidate, GSBR-1290, is a GLP-1 receptor agonist for the treatment of obesity and type 2 diabetes. The company’s preclinical drug development pipeline necessitates animal testing for regulatory compliance and research, as is standard for pharmaceutical and biotech entities advancing novel compounds into human trials.

Animal Exploitation
Since Jan 3, 2022

Structure Therapeutics is a biotechnology company whose core business model involves conducting animal testing as part of its drug discovery and development process. The company's pipeline of small-molecule therapeutics, including candidates for obesity and metabolic diseases, requires preclinical testing in animal models to assess efficacy and safety before human trials can begin. This reliance on animal experimentation is standard practice in the pharmaceutical industry but constitutes commercial exploitation of animals under the firm's exclusion policy.

While the company may adhere to institutional animal care and use committee (IACUC) protocols, the fundamental activity remains the use of animals as a research tool. There is no public evidence that Structure Therapeutics is pursuing a wholesale alternative to animal testing or has made a commitment to replace animal models with advanced non-animal methodologies. The exclusion reflects the company's operational dependence on animal testing to advance its product candidates.

Research Sources 10 organizations

Wondering what we do invest in?

The Naughty List

A digest of changes to our exclusion list — new additions, removals, and the evidence behind them. We review the list continuously as new evidence surfaces.

RSS feed No spam · Unsubscribe anytime

Companies appear on our exclusion list based on our investment judgment — not because they've done anything illegal. This is a difference of values and opinion, not an accusation of wrongdoing. Exclusion does not constitute a recommendation against investing in any company, and absence from the list does not constitute a recommendation to invest.

This information is provided for educational and transparency purposes only and should not be relied upon as investment advice. Data is drawn from independent watchdogs, NGOs, government registries, and Ethical Capital's ongoing research — see Research Sources for the full list.

Ethical Capital LLC is a state-registered investment adviser in Utah (CRD #316032). Registration does not imply a certain level of skill or training.