Motus GI Holdings, Inc.

Motus GI Holdings, Inc. is a medical device company whose flagship product, the Pure-Vu System, is cleared by the FDA for use in colonoscopy procedures. The system's development and regulatory testing involved animal subjects. The company's SEC filings detail a pre-clinical testing program that utilized porcine (pig) models to demonstrate the safety and efficacy of the device prior to human trials. This commercial use of animals in product development falls under the animal exploitation exclusion criteria.

While the use of animal models is a common regulatory pathway for medical devices, the exclusion reflects a principle against commercial ventures that rely on the exploitation of animals. The available evidence from Cruelty Free Investors and SEC filings indicates animal testing was integral to bringing the Pure-Vu System to market, but does not provide specific details on the scale, conditions, or sourcing of animals used.