This page is part of our public exclusion list — a transparency tool that shows which companies we screen out and why. It is not investment advice, and it is not an accusation. But it is subject to change as our understanding of the facts evolves.
Mannatech manufactures and sells glyconutrient dietary supplements through a multi-level marketing model, with its flagship Ambrotose product line. The company has conducted or commissioned animal testing to support safety and efficacy claims for its supplement formulations. Published studies include rat models demonstrating effects of Ambrotose Complex and Advanced Ambrotose on chemically induced colitis, acemannan bone health studies in animal assays, and investigations of plant polysaccharide supplements on GI tract cytokines in normal and DSS-treated rats. Mannatech researchers presented these animal study findings at scientific conferences including the Scripps Center for Integrative Medicine conference. The company has faced significant scientific criticism: three Nobel laureates demanded Mannatech stop using their names to promote glyconutrient sales, and the Texas Attorney General accused the company of violating the Texas Deceptive Practices Act in 2007.
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Companies appear on our exclusion list based on our investment judgment — not because they've done anything illegal. This is a difference of values and opinion, not an accusation of wrongdoing. Exclusion does not constitute a recommendation against investing in any company, and absence from the list does not constitute a recommendation to invest.
This information is provided for educational and transparency purposes only and should not be relied upon as investment advice. Data is drawn from independent watchdogs, NGOs, government registries, and Ethical Capital's ongoing research — see Research Sources for the full list.
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