PAVmed Inc.

PAVmed Inc. is a medical device company whose product development pipeline requires animal testing as a core component of its regulatory compliance process. The company’s Form 10-K filings explicitly state that an Investigational Device Exemption (IDE) application to the FDA “must be supported by appropriate data, such as animal and laboratory test results.” This indicates animal studies are a standard, required step in the safety testing of its devices prior to human clinical trials.

The company’s public research includes collaborations on biomarker validation that utilize animal models, and its participation in a medical technologies innovation hub listed “large animal models for immune safety testing” as part of its pre-clinical work. As a developer of novel medical devices, PAVmed operates within a sector where animal testing is typically mandated by regulatory authorities for market approval, constituting a funded and outsourced animal testing operation.