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SEPTERNA INC

SEPN

Health Care

1

exclusion reason

1 theme

Animal Welfare (1)
SEPN Health Care Current as of March 2026

This page is part of our public exclusion list — a transparency tool that shows which companies we screen out and why. It is not investment advice, and it is not an accusation. But it is subject to change as our understanding of the facts evolves.

Animal Testing & Research
Since Mar 12, 2026

Septerna Inc. is a clinical-stage biotechnology company whose research and development pipeline is built on preclinical animal testing. The company’s drug discovery platform targets G protein-coupled receptors (GPCRs), a class of proteins traditionally investigated using in vivo models. Its SEC filings explicitly reference “long-term preclinical testing, such as animal tests” as part of its development process. As a company with no approved products, its entire value proposition and pipeline advancement are currently dependent on animal-based research.

The company is listed by Cruelty Free Investors on its “Animal Usage: Animal Testing” roster, which flags biotechnology and pharmaceutical firms whose operations involve animal exploitation. Septerna’s business model is intrinsically linked to the use of animals in research, placing it within the broad category of commercial animal exploitation for product development.

Research Sources 1 organization
Cruelty Free Investors
External

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Companies appear on our exclusion list based on our investment judgment — not because they've done anything illegal. This is a difference of values and opinion, not an accusation of wrongdoing. Exclusion does not constitute a recommendation against investing in any company, and absence from the list does not constitute a recommendation to invest.

This information is provided for educational and transparency purposes only and should not be relied upon as investment advice. Data is drawn from independent watchdogs, NGOs, government registries, and Ethical Capital's ongoing research — see Research Sources for the full list.

Ethical Capital LLC is a state-registered investment adviser in Utah (CRD #316032). Registration does not imply a certain level of skill or training.