This page is part of our public exclusion list — a transparency tool that shows which companies we screen out and why. It is not investment advice, and it is not an accusation. But it is subject to change as our understanding of the facts evolves.
Synlogic, Inc. is a clinical-stage biotechnology company developing synthetic biotic medicines, which are engineered strains of bacteria designed to treat diseases by performing metabolic functions in the gut. This research and development process relies on animal testing. The company's pipeline candidates, such as SYNB1353 for homocystinuria and SYNB1020 for hyperammonemia, have progressed through preclinical studies in animal models, as documented in peer-reviewed publications. Synlogic is explicitly listed by Cruelty Free Investors as a company that exploits animals, categorized under "Animal Usage: Animal Testing." As a biotech firm with no marketed products, its core research activity is contingent on animal experimentation to advance its therapeutic candidates toward human clinical trials.
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A digest of changes to our exclusion list — new additions, removals, and the evidence behind them. We review the list continuously as new evidence surfaces.
Companies appear on our exclusion list based on our investment judgment — not because they've done anything illegal. This is a difference of values and opinion, not an accusation of wrongdoing. Exclusion does not constitute a recommendation against investing in any company, and absence from the list does not constitute a recommendation to invest.
This information is provided for educational and transparency purposes only and should not be relied upon as investment advice. Data is drawn from independent watchdogs, NGOs, government registries, and Ethical Capital's ongoing research — see Research Sources for the full list.
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