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VYNE THERAPEUTICS INC

VYNE

Health Care

3

exclusion reasons

2 themes

Corporate Misconduct (2) Animal Welfare (1)
VYNE Health Care Current as of March 2026

This page is part of our public exclusion list — a transparency tool that shows which companies we screen out and why. It is not investment advice, and it is not an accusation. But it is subject to change as our understanding of the facts evolves.

Regulatory Violations
Since Mar 19, 2026

VYNE Therapeutics received an FDA clinical hold on VYN202 in April 2025 after testicular toxicity was found in preclinical dog studies. The company also failed Nasdaq listing standards, compounding regulatory failures.

Financial Misconduct
Since Mar 19, 2026

Discontinued Repibresib after Phase 2b failure, then pivoted to merger strategy. Pattern of misleading investors about pipeline viability and corporate direction.

Animal Testing & Research
Since Mar 12, 2026

VYNE Therapeutics develops drugs for immuno-inflammatory conditions. A clinical hold was placed on its lead program after a safety signal emerged in dog studies, confirming active animal testing. Cruelty Free Investors lists VYNE under animal testing.

Research Sources 6 organizations

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A digest of changes to our exclusion list — new additions, removals, and the evidence behind them. We review the list continuously as new evidence surfaces.

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Companies appear on our exclusion list based on our investment judgment — not because they've done anything illegal. This is a difference of values and opinion, not an accusation of wrongdoing. Exclusion does not constitute a recommendation against investing in any company, and absence from the list does not constitute a recommendation to invest.

This information is provided for educational and transparency purposes only and should not be relied upon as investment advice. Data is drawn from independent watchdogs, NGOs, government registries, and Ethical Capital's ongoing research — see Research Sources for the full list.

Ethical Capital LLC is a state-registered investment adviser in Utah (CRD #316032). Registration does not imply a certain level of skill or training.