Xencor, Inc. is screened out under 2 exclusion reasons spanning 1 issue category.
This page is part of our public exclusion list — a transparency tool that shows which companies we screen out and why. It is not investment advice, and it is not an accusation. It is a statement of values.
Xencor, Inc. is a clinical-stage biopharmaceutical company that develops engineered monoclonal antibody and cytokine therapies to treat cancer and autoimmune diseases. As part of its preclinical research and development process, the company conducts animal testing to evaluate the safety and efficacy of its drug candidates. This testing is a standard, required component of the regulatory pathway for bringing new therapeutics to market. Cruelty Free Investors, which maintains a list of companies involved in animal exploitation, specifically flags Xencor for its animal testing activities.
Xencor, Inc. develops bispecific and engineered antibody therapies for cancer and autoimmune diseases, a process that requires animal testing to meet regulatory standards for safety and efficacy. The company’s public filings consistently reference preclinical animal studies as a core component of its research and development pipeline. For example, its 2022 and 2024 Annual Reports on Form 10-K explicitly cite the completion of animal studies as part of its standard preclinical testing regimen.
While some third-party assessments note the company may have policies limiting discretionary testing, the fundamental requirement for animal data in the drug approval process overrides such restrictions. As a biotechnology firm advancing therapeutic candidates through clinical trials, Xencor’s business model is intrinsically dependent on animal testing to satisfy regulatory mandates from agencies like the U.S. Food and Drug Administration.
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Companies appear on our exclusion list based on our investment judgment — not because they've done anything illegal. This is a difference of values and opinion, not an accusation of wrongdoing. Exclusion does not constitute a recommendation against investing in any company, and absence from the list does not constitute a recommendation to invest.
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